Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | RBP4 | P02753 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953013 | 0.99 | HTR2C (0.44) | HTR2CHTR2AHTR2BRBP4PTGDR2 | |
| SCHEMBL15068105 | 0.94 | HTR2A (0.50) | HTR2CHTR2AHTR2BRBP4BRD4 | |
| SCHEMBL13722614 | 0.87 | HTR2A (0.45) | HTR2CHTR2AHTR2BRBP4SCN9A | |
| SCHEMBL29953902 | 0.84 | PTGDR2 (0.41) | PTGDR2PARP10SLC6A4HTR6PDE4B | |
| SCHEMBL16034960 | 0.83 | HTR2A (0.48) | HTR2CHTR2AHTR2BRBP4BRD4 | |
| SCHEMBL29954206 | 0.82 | PTGDR2 (0.43) | PTGDR2PARP10SLC6A4HTR6 | |
| SCHEMBL29951542 | 0.81 | TSHR (0.45) | SCN9A | |
| SCHEMBL24224805 | 0.80 | HPGD (0.49) | HTR2CHTR2AHTR2BSLC6A4HTR6 | |
| SCHEMBL29957281 | 0.80 | LIPE (0.50) | HTR2CPARP10MCHR1 | |
| SCHEMBL29954455 | 0.80 | TSHR (0.48) | SCN9ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |