Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954206 | 0.98 | PTGDR2 (0.43) | PTGDR2HPGDLMNAXDHSLC6A4 | |
| SCHEMBL29956630 | 0.87 | XDH (0.41) | HPGDLMNAXDHNPC1RAB9A | |
| SCHEMBL29951637 | 0.84 | HTR2C (0.45) | PTGDR2SLC6A4HTR6PARP10PDE4B | |
| SCHEMBL29953013 | 0.82 | HTR2C (0.44) | PTGDR2SLC6A4HTR6PARP15PARP10 | |
| SCHEMBL29955998 | 0.81 | RAB9A (0.46) | HPGDLMNANPC1RAB9A | |
| SCHEMBL16172630 | 0.81 | HPGD (0.54) | PTGDR2HPGDLMNASLC6A4HTR6 | |
| SCHEMBL29953399 | 0.79 | RAB9A (0.50) | HPGDLMNANPC1RAB9A | |
| SCHEMBL18374449 | 0.78 | PARP10 (0.42) | HPGDSLC6A4HTR6PARP15PARP10 | |
| SCHEMBL29957281 | 0.78 | LIPE (0.50) | HPGDPARP15PARP10C5AR1 | |
| SCHEMBL15068105 | 0.77 | HTR2A (0.50) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |