Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.55 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2056065 | 1.00 | KEAP1 (0.65) | KEAP1HDAC2HDAC8HDAC6HTT | |
| SCHEMBL30989152 | 0.85 | CYP19A1 (0.63) | HTTLMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29285993 | 0.85 | CYP19A1 (0.63) | HTTLMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5651347 | 0.84 | KEAP1 (0.74) | KEAP1HDAC2HDAC8HDAC6HTT | |
| SCHEMBL7354552 | 0.81 | KEAP1 (0.69) | KEAP1HDAC2HDAC8HDAC6HTT | |
| SCHEMBL4061585 | 0.81 | KEAP1 (0.69) | KEAP1HDAC2HDAC8HDAC6HTT | |
| SCHEMBL407414 | 0.80 | KEAP1 (1.00) | KEAP1HDAC2HDAC8HDAC6HTT | |
| SCHEMBL14025561 | 0.80 | KEAP1 (0.71) | KEAP1HDAC2HDAC8HDAC6HTT | |
| SCHEMBL934547 | 0.80 | KMT2A (0.47) | HTTLMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4070835 | 0.79 | HDAC2 (0.77) | KEAP1HDAC2HDAC8HDAC6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4602046-A1 | SUBSTITUTED FUROPYRIDINES FOR THERAPEUTIC USE | Masarykova Univerzita (CZ) | 2025-08-20 | — | — | EP | disclosed |
| WO-2024078649-A1 | SUBSTITUTED FUROPYRIDINES FOR THERAPEUTIC USE | MASARYKOVA UNIVERZITA (CZ) | 2024-04-18 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |