SCHEMBL29951680

SCHEMBL29951680

NCc1ncc(C=O)cn1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KCNJ1 P48048 1/20 0.35
ALDH1A1 P00352 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KDM4E B2RXH2 1/20 0.32
CYP2A6 P11509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29956984 0.98 KCNJ1 (0.34) KCNJ1ALDH1A1L3MBTL1KDM4E
SCHEMBL15332698 0.81 HRH1 (0.33) KCNJ1ALDH1A1L3MBTL1KDM4E
Hydrochloric Acid SCHEMBL29956780 0.79 HRH4 (0.32)
SCHEMBL29951446 0.75 HSD17B10 (0.33) KCNJ1ALDH1A1L3MBTL1KDM4ECYP2A6
SCHEMBL13447382 0.75 ALDH1A1 (0.35) KCNJ1ALDH1A1L3MBTL1KDM4ECYP2A6
SCHEMBL29952918 0.75 ALDH1A1 (0.37) KCNJ1ALDH1A1L3MBTL1KDM4ECYP2A6
SCHEMBL1134013 0.75 ALDH1A1 (0.37) KCNJ1ALDH1A1L3MBTL1KDM4ECYP2A6
SCHEMBL5901003 0.75 ALDH1A1 (0.32) KCNJ1ALDH1A1L3MBTL1KDM4ECYP2A6
SCHEMBL528074 0.74
SCHEMBL15331879 0.73 HTT (0.42) ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed