SCHEMBL528074

SCHEMBL528074

Nc1ncc(C=O)cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28816399 0.97 HDAC1 (0.37)
SCHEMBL8625648 0.74 ALDH1A1 (0.35)
SCHEMBL1647573 0.74 HDAC1 (0.35)
SCHEMBL29951680 0.74 KCNJ1 (0.35)
SCHEMBL19541390 0.72
SCHEMBL21993012 0.72
SCHEMBL7944939 0.72
SCHEMBL5433410 0.72
SCHEMBL789028 0.72
SCHEMBL4468172 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117110483-A Liquid chromatographic analysis and detection method for 5-pyrimidine formaldehyde compounds 常州合全药业有限公司 2023-11-24 CN claimed
CN-110461833-A 2- amino -5- oxygroup alkyl derivative and its purposes for preventing and treating undesirable plant growth BAYER CROPSCIENCE AG 2019-11-15 CN claimed
WO-2008133344-A2 PIPERIDINE DERIVATIVE AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-11-06 WO claimed
US-20080275085-A1 Piperidine derivative and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-11-06 US claimed
US-5648490-A Process for the preparation of 5-formylaminopyrimidines SKW TROSTBERG AKTIENGESELLSCHAFT (DE) 1997-07-15 US claimed
US-12617801-B2 Tetrahydrothieno pyridine derivatives as DDRS inhibitors CHIESI FARMACEUTICI S.P.A. (IT) 2026-05-05 US disclosed
EP-4313292-B1 INDOLINE DERIVATIVES AS DDR1 AND DDR2 INHIBITORS CHIESI FARM SPA (IT) 2026-02-18 EP disclosed
US-20260034105-A1 Generative AI-Assisted Identification of Novel PI3K-alpha Inhibitors THE FIRST AFFILIATED HOSPITAL OF XI'AN JIAOTONG UNIVERSITY (CN) 2026-02-05 US disclosed
CN-117110483-B Liquid chromatographic analysis and detection method for 5-pyrimidine formaldehyde compounds 常州合全药业有限公司 2025-11-18 CN disclosed
WO-2025128616-A1 COMPOUNDS FOR TREATING CANCER GENESIS THERAPEUTICS, INC. (US) 2025-06-19 WO disclosed
CN-120058674-A 4 (1H-pyrazol-3-yl) piperidinyl derivative, preparation method thereof and application thereof in preparation of MNK inhibitor 烟台新药创制山东省实验室 2025-05-30 CN disclosed
EP-4313994-B1 TETRAHYDROTHIENO PYRIDINE DERIVATIVES AS DDRS INHIBITORS CHIESI FARM SPA (IT) 2025-03-05 EP disclosed
US-20070032495-A1 Pyrazolotriazines as kinase inhibitors MERCK SHARP & DOHME LLC 2007-02-08 US disclosed
US-7166602-B2 Pyrazolotriazines as kinase inhibitors SCHERING CORPORATION (US) 2007-01-23 US disclosed
US-7166602-B2 Pyrazolotriazines as kinase inhibitors SCHERING CORPORATION (US) 2007-01-23 US disclosed
US-7161003-B1 Pyrazolopyrimidines as cyclin dependent kinase inhibitors SCHERING CORPORATION (US) 2007-01-09 US disclosed
US-7161003-B1 Pyrazolopyrimidines as cyclin dependent kinase inhibitors SCHERING CORPORATION (US) 2007-01-09 US disclosed
US-20060293503-A1 Polyaminopyridines and method for producing same SUMITOMO SEIKA CHEMICALS CO., LTD (JP) 2006-12-28 US disclosed
EP-1669390-A1 POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2006-06-14 EP disclosed
EP-0325131-A2 Pyrimidine derivatives as performance stimulating agents BAYER AG (DE) 1989-07-26 EP disclosed