Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1249895 | 1.00 | AHR (0.59) | AHRMEN1MAPTKMT2AHTT | |
| SCHEMBL16572864 | 0.84 | KIF11 (0.43) | AHRMEN1MAPTKMT2AHTT | |
| SCHEMBL29951170 | 0.82 | AHR (0.59) | AHRMEN1MAPTKMT2AKIF11 | |
| SCHEMBL9274962 | 0.82 | AHR (0.59) | AHRMEN1MAPTKMT2AHTT | |
| SCHEMBL9613106 | 0.81 | KIF11 (0.41) | AHRMEN1MAPTKMT2AHTT | |
| SCHEMBL6592979 | 0.81 | AHR (0.66) | AHRMEN1MAPTKMT2AKIF11 | |
| SCHEMBL24031443 | 0.79 | KIF11 (0.40) | AHRMEN1MAPTKMT2AHTT | |
| SCHEMBL28235853 | 0.79 | AHR (0.56) | AHRMEN1MAPTKMT2AHTT | |
| SCHEMBL28137898 | 0.79 | AHR (0.56) | AHRMEN1MAPTKMT2AHTT | |
| SCHEMBL28137902 | 0.79 | AHR (0.56) | AHRMEN1MAPTKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |