Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ABL2 | P42684 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622184 | 0.77 | MAPT (0.36) | TTRKDM4ERAB9ASNCA | |
| SCHEMBL8566803 | 0.76 | ALOX15 (0.44) | KDM4ERAB9A | |
| SCHEMBL29956980 | 0.75 | XDH (0.54) | XDHALDH5A1ABATERN1TTR | |
| SCHEMBL7494690 | 0.74 | SMN1; SMN2 (0.42) | KDM4ERAB9A | |
| SCHEMBL5582938 | 0.74 | MAPK1 (0.36) | ALDH5A1ABATTTRKDM4ERAB9A | |
| SCHEMBL2586421 | 0.74 | MAPT (0.41) | ERN1TTRKDM4ERAB9ASNCA | |
| SCHEMBL12179353 | 0.74 | MAPT (0.34) | TTRKDM4ERAB9ASNCA | |
| SCHEMBL2340132 | 0.74 | KDM4E (0.38) | TTRKDM4E | |
| SCHEMBL21484861 | 0.72 | KDM4E (0.46) | XDHALDH5A1ABATERN1PTGS2 | |
| SCHEMBL488755 | 0.71 | TPMT (0.44) | PTGS2KDM4ESNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |