Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554836 | 0.93 | KDM4E (0.69) | KDM4ERAB9AALDH1A1MTNR1AMTNR1B | |
| SCHEMBL29953639 | 0.91 | KDM4E (0.54) | KDM4ERAB9AALDH1A1MTNR1AMTNR1B | |
| SCHEMBL29952430 | 0.88 | RAB9A (0.72) | KDM4ERAB9AALDH1A1KMT2ATSHR | |
| SCHEMBL15331584 | 0.87 | RAB9A (0.64) | KDM4ERAB9AALDH1A1KMT2ATSHR | |
| SCHEMBL2553637 | 0.85 | KDM4E (0.61) | KDM4ERAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL29954513 | 0.84 | NPSR1 (0.52) | KDM4ERAB9AALDH1A1KMT2ATSHR | |
| SCHEMBL15332397 | 0.83 | KDM4E (0.56) | KDM4ERAB9AALDH1A1MTNR1AMTNR1B | |
| SCHEMBL2554953 | 0.82 | KDM4E (0.71) | KDM4ERAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL2556788 | 0.82 | RAB9A (0.64) | KDM4ERAB9AALDH1A1MTNR1AMTNR1B | |
| SCHEMBL2560184 | 0.82 | RAB9A (0.64) | KDM4ERAB9AALDH1A1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |