Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14066214 | 0.88 | PTGDR2 (0.60) | PTGDR2KDM4ESMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL15296803 | 0.88 | ABCB1 (0.55) | PTGDR2ABCB1LMNAMAPTHTT | |
| SCHEMBL18791370 | 0.87 | PTGDR2 (0.56) | PTGDR2KDM4ELMNAMAPTHTT | |
| SCHEMBL14273072 | 0.85 | PTGDR2 (0.57) | PTGDR2KDM4ESMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL11263623 | 0.84 | KDM4E (0.53) | PTGDR2ABCB1KDM4ELMNAMAPT | |
| SCHEMBL11637091 | 0.83 | ABCB1 (0.56) | PTGDR2ABCB1LMNAMAPTHTT | |
| SCHEMBL3065130 | 0.83 | CYP3A4 (0.62) | PTGDR2ABCB1KDM4ELMNAMAPT | |
| SCHEMBL320418 | 0.82 | PTGDR2 (0.66) | PTGDR2KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL718460 | 0.82 | PTGDR2 (0.68) | PTGDR2HTTSMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL3691062 | 0.82 | PTGDR2 (0.68) | PTGDR2MAPTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |