Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363092 | 0.93 | L3MBTL1 (0.67) | PTGDR2KDM4ETDP1POLBSMN1; SMN2 | |
| SCHEMBL5275178 | 0.91 | POLB (0.64) | PTGDR2KDM4ETDP1POLBSMN1; SMN2 | |
| SCHEMBL17269686 | 0.91 | POLB (0.64) | PTGDR2KDM4ETDP1POLBSMN1; SMN2 | |
| SCHEMBL1324243 | 0.87 | TDP1 (0.70) | PTGDR2KDM4ETDP1TSHRCYP2C19 | |
| SCHEMBL3064143 | 0.87 | TSHR (0.70) | PTGDR2KDM4ETDP1POLBSMN1; SMN2 | |
| SCHEMBL2113005 | 0.87 | PTGDR2 (0.64) | PTGDR2KDM4ETDP1POLBSMN1; SMN2 | |
| SCHEMBL22434874 | 0.85 | PTGDR2 (0.55) | PTGDR2KDM4ETDP1POLBSMN1; SMN2 | |
| SCHEMBL2717225 | 0.85 | PTGDR2 (0.62) | PTGDR2KDM4ETDP1POLBSMN1; SMN2 | |
| SCHEMBL14273070 | 0.84 | PTGDR2 (0.56) | PTGDR2KDM4ETDP1POLBSMN1; SMN2 | |
| SCHEMBL9912420 | 0.84 | FFAR1 (0.61) | PTGDR2KDM4EPKMFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160108031-A1 | INHIBITORS OF NHR2 AND/OR RUNX1/ETO-TETRAMERIZATION | HEINRICH-HEINE-UNIVERSITAT DUSSELDORF (DE) | 2016-04-21 | — | — | US | claimed |
| EP-2991963-A2 | INHIBITORS OF NHR2 AND/OR RUNX1/ETO-TETRAMERIZATION | Heinrich-Heine-Universität Düsseldorf (DE) | 2016-03-09 | — | — | EP | claimed |
| WO-2014177464-A2 | INHIBITORS OF NHR2 AND/OR RUNX1/ETO-TETRAMERIZATION | HEINRICH-HEINE-UNIVERSITÄT DÜSSELDORF (DE) | 2014-11-06 | — | — | WO | claimed |
| EP-2991963-B1 | INHIBITORS OF NHR2 AND/OR RUNX1/ETO-TETRAMERIZATION | HEINRICH HEINE UNIV DUESSELDORF (DE) | 2021-07-07 | — | — | EP | disclosed |
| EP-2991963-B1 | INHIBITORS OF NHR2 AND/OR RUNX1/ETO-TETRAMERIZATION | HEINRICH HEINE UNIV DUESSELDORF (DE) | 2021-07-07 | — | — | EP | disclosed |
| US-20210147415-A1 | INHIBITORS OF NHR2 AND/OR RUNX1/ETO-TETRAMERIZATION | HEINRICH-HEINE-UNIVERSITÄT DÜSSELDORF (DE) | 2021-05-20 | — | — | US | disclosed |
| US-20210147415-A1 | INHIBITORS OF NHR2 AND/OR RUNX1/ETO-TETRAMERIZATION | HEINRICH-HEINE-UNIVERSITÄT DÜSSELDORF (DE) | 2021-05-20 | — | — | US | disclosed |
| EP-2590642-B1 | PKC ACTIVATORS AND ANTICOAGULANT IN REGIMEN FOR TREATING STROKE | ALKON DANIEL L (US) | 2018-03-14 | — | — | EP | disclosed |
| US-9889183-B2 | PKC activators and anticoagulant in regimen for treating stroke | WEST VIRGINIA UNIVERSITY (US) | 2018-02-13 | — | — | US | disclosed |
| EP-1975707-B1 | Curable composition and planographic printing plate precursor | FUJIFILM CORP (JP) | 2017-07-19 | — | — | EP | disclosed |
| EP-1801651-B1 | Polymerizable composition and planographic printing plate precursor using the same | FUJIFILM CORP (JP) | 2017-04-19 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-5942372-A | COMPRISED A SPECTRAL SENSITIZER THAT SENSITIZES IN THE ULTRAVIOLET OR VISIBLE REGIONS OF THE SPECTRUM AND AN N-ARYL POLYCARBOXYLIC ACID CO-INITIATOR; VERY HIGH PHOTOSPEED AND VERY GOOD SHELF-LIFE IN COMPUTER-TO-PLATE SYSTEMS | KODAK POLYCHROME GRAPHICS, LLC (US) | 1999-08-24 | — | — | US | disclosed |
| US-5914215-A | ELEMENT COMPRISING SUPPORT HAVING PHOTOIMAGEABLE, RADIATION SENSITIVE LAYER COMPRISING UNSATURATED COMPOUND, PHOTOINITIATOR SYSTEM COMPRISING SENSITIZER SENSITIZING IN ULTRAVIOLET OR VISIBLE REGION OF SPECTRUM, CO-INITIATOR | KODAK POLYCHROME GRAPHIC, LLC (US) | 1999-06-22 | — | — | US | disclosed |
| US-5888700-A | NONFOGGING, SHELF LIFE | KODAK POLYCHROME GRPAHICS, LLC (US) | 1999-03-30 | — | — | US | disclosed |
| US-5821030-A | DIRECT DIGITAL EXPOSURE; HIGH WRITING SPEED; ADHESION; ANTIFOGGING AGENTS; SHELF LIFE; USING A POLYCARBOXYLIC ACID IN THE PHOTOPOLYMERIZATION INITIATOR SYSTEM AND A BASIC COMPOUND IN THE OXYGEN BARRIER LAYER | KODAK POLYCHROME GRAPHICS (US) | 1998-10-13 | — | — | US | disclosed |
| US-5776655-A | CONTAINING PHOTOPOLYMER | EASTMAN KODAK COMPANY (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0795790-A2 | Peel-developable lithographic printing plate | EASTMAN KODAK COMPANY (US) | 1997-09-17 | — | — | EP | disclosed |
| US-5629354-A | Photopolymerization initiator system comprising a spectral sensitizer and a polycarboxylic acid co-initiator | EASTMAN KODAK COMPANY (US) | 1997-05-13 | — | — | US | disclosed |
| EP-0730201-A1 | Sensitized photopolymerizable compositions and use thereof in lithographic printing plates | EASTMAN KODAK COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108031-A1 | INHIBITORS OF NHR2 AND/OR RUNX1/ETO-TETRAMERIZATION | RUNX1, ETV6, NPM1 | PTGDR2 2294/4885KDM4E 2323/4885TDP1 1645/4885 |
| US-20210147415-A1 | INHIBITORS OF NHR2 AND/OR RUNX1/ETO-TETRAMERIZATION | RUNX1, ETV6, NPM1 | PTGDR2 2294/4885KDM4E 2323/4885TDP1 1645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.