SCHEMBL3065130

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11637091	0.86	ABCB1 (0.56)	CYP3A4TSHRABCB1LMNAMAPT
	SCHEMBL1641613	0.86	TSHR (0.57)	CYP3A4TSHRLMNAMAPTL3MBTL1
	SCHEMBL4276935	0.86	TSHR (0.62)	CYP3A4TSHRABCB1LMNAMAPT
	SCHEMBL16956293	0.85	MAPT (0.45)	CYP3A4TSHRABCB1LMNAMAPT
	SCHEMBL15423768	0.84	KCNMA1 (0.48)	CYP3A4TSHRABCB1LMNAMAPT
	SCHEMBL7860492	0.84	MAPK1 (0.51)	CYP3A4TSHRLMNAMAPTHTT
	SCHEMBL15296803	0.84	ABCB1 (0.55)	CYP3A4TSHRABCB1LMNAMAPT
	SCHEMBL14279020	0.84	TSHR (0.52)	TSHRLMNAMAPTL3MBTL1HTT
	Zinc Ion SCHEMBL9187537	0.84	KCNMA1 (0.48)	CYP3A4TSHRABCB1LMNAMAPT
	SCHEMBL9187547	0.84	TSHR (0.56)	TSHRLMNAMAPTL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.