Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.52 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | IAPP | P10997 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | DDO | Q99489 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1527075 | 1.00 | GABRA1 (0.52) | GABRA1GABRB2ERN1IAPPCA1 | |
| SCHEMBL7090370 | 0.91 | GABRA1 (0.44) | GABRA1GABRB2ERN1IAPPCA1 | |
| SCHEMBL1527068 | 0.86 | IAPP (0.44) | GABRA1GABRB2IAPP | |
| SCHEMBL5429057 | 0.85 | HSPA5 (0.50) | GABRA1GABRB2ERN1CA1CA2 | |
| SCHEMBL320588 | 0.84 | GABRA1 (0.50) | GABRA1GABRB2 | |
| SCHEMBL1527069 | 0.83 | BID (0.50) | IAPPTSHR | |
| SCHEMBL11771453 | 0.83 | GABRA1 (0.52) | GABRA1GABRB2IAPPCA1CA2 | |
| SCHEMBL4709719 | 0.83 | ERN1 (0.46) | GABRA1GABRB2ERN1CA2TRIM24 | |
| SCHEMBL1527143 | 0.82 | BID (0.56) | IAPP | |
| SCHEMBL4390000 | 0.82 | ERN1 (0.41) | GABRA1GABRB2ERN1IAPPCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |