Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951885 | 0.91 | GABRA1 (0.52) | GABRA1GABRB2CA12CA1CA2 | |
| SCHEMBL1527075 | 0.91 | GABRA1 (0.52) | GABRA1GABRB2CA12CA1CA2 | |
| SCHEMBL28257757 | 0.87 | TRPA1 (0.50) | TRPA1ATMMAPTCA1CA2 | |
| SCHEMBL412923 | 0.87 | TRPA1 (0.50) | TRPA1ATMMAPTCA1CA2 | |
| SCHEMBL29485033 | 0.87 | TRPA1 (0.50) | TRPA1ATMMAPTCA1CA2 | |
| SCHEMBL606253 | 0.85 | GABRA1 (0.43) | GABRA1GABRB2TP53HSD17B10PKM | |
| Potassium Ion SCHEMBL28720832 | 0.83 | TRPA1 (0.46) | TRPA1ATMMAPTCA1CA2 | |
| SCHEMBL16704711 | 0.81 | ERN1 (0.47) | TRPA1ATMMAPTCA1CA2 | |
| Phenol SCHEMBL8416132 | 0.79 | CYP1A2 (0.45) | TRPA1ATMMAPTHSD17B10CA12 | |
| SCHEMBL1527068 | 0.79 | IAPP (0.44) | GABRA1GABRB2MAPTHSD17B10IAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334107-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002032908-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2002-04-25 | — | — | WO | disclosed |