Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 13/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27003696 | 1.00 | PTPN1 (0.49) | PTPN1MEN1POLBKMT2AGPR35 | |
| SCHEMBL28262152 | 0.83 | PTPN1 (0.65) | PTPN1MEN1POLBKMT2AMAOA | |
| SCHEMBL29956402 | 0.83 | PTPN1 (0.65) | PTPN1MEN1POLBKMT2AMAOA | |
| SCHEMBL27003687 | 0.83 | PTPN1 (0.65) | PTPN1MEN1POLBKMT2AGPR35 | |
| SCHEMBL29954633 | 0.83 | PTPN1 (0.50) | PTPN1MEN1POLBKMT2AMAOA | |
| SCHEMBL5373635 | 0.79 | PTPN1 (0.54) | PTPN1MEN1POLBKMT2AMAOA | |
| SCHEMBL29952203 | 0.77 | PTPN1 (0.55) | PTPN1MEN1POLBKMT2AGPR35 | |
| SCHEMBL23887130 | 0.77 | PTPN1 (0.72) | PTPN1MEN1POLBKMT2AMAOA | |
| SCHEMBL28263226 | 0.71 | LMNA (0.47) | MEN1KMT2AGPR35CYP3A4KDM4E | |
| SCHEMBL13978677 | 0.69 | PTPN1 (0.50) | PTPN1MEN1POLBKMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |