Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 13/20 | 0.65 |
| ▸ | TPST2 | O60704 | 1/20 | 0.43 |
| ▸ | SULT1E1 | P49888 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956402 | 1.00 | PTPN1 (0.65) | PTPN1TPST2SULT1E1MEN1KMT2A | |
| SCHEMBL29954633 | 0.83 | PTPN1 (0.50) | PTPN1TPST2SULT1E1MEN1KMT2A | |
| SCHEMBL27003687 | 0.83 | PTPN1 (0.65) | PTPN1TPST2SULT1E1MEN1KMT2A | |
| SCHEMBL29951925 | 0.83 | PTPN1 (0.49) | PTPN1MEN1KMT2APOLBMAOA | |
| SCHEMBL27003696 | 0.83 | PTPN1 (0.49) | PTPN1MEN1KMT2APOLBMAOA | |
| SCHEMBL5708656 | 0.79 | PTPN1 (1.00) | PTPN1TPST2SULT1E1MEN1KMT2A | |
| SCHEMBL29952203 | 0.77 | PTPN1 (0.55) | PTPN1MEN1KMT2APOLBMAOA | |
| SCHEMBL29955707 | 0.77 | PTPN1 (0.72) | PTPN1TPST2SULT1E1MEN1KMT2A | |
| SCHEMBL29956932 | 0.74 | PTPN1 (0.68) | PTPN1TPST2SULT1E1MEN1KMT2A | |
| SCHEMBL13978677 | 0.69 | PTPN1 (0.50) | PTPN1MEN1KMT2APOLBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106316999-B | A kind of preparation method and application of two ketoximes derivatives of benzofuran -2,3- | 江苏强盛功能化学股份有限公司 | 2019-01-08 | — | — | CN | disclosed |