Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.30 |
| ▸ | KDR | P35968 | 3/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.30 |
| ▸ | AURKA | O14965 | 2/20 | 0.30 |
| ▸ | RET | P07949 | 2/20 | 0.30 |
| ▸ | FLT1 | P17948 | 2/20 | 0.30 |
| ▸ | FLT3 | P36888 | 2/20 | 0.30 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.30 |
| ▸ | STK3 | Q13188 | 2/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.30 |
| ▸ | GAK | O14976 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6090987 | 0.84 | CHEK1 (0.51) | CHEK1ALDH1A1KMT2APOLBRAB9A | |
| SCHEMBL6088742 | 0.82 | KDM4E (0.46) | CHEK1ALDH1A1KMT2APOLBKDM4E | |
| SCHEMBL6090420 | 0.81 | CHEK1 (0.43) | CHEK1ALDH1A1KMT2APOLBKDM4E | |
| SCHEMBL5358334 | 0.81 | ALDH1A1 (0.39) | CHEK1ALDH1A1KMT2APOLBRAB9A | |
| SCHEMBL6088532 | 0.79 | CHEK1 (0.34) | CHEK1ALDH1A1KMT2APOLB | |
| SCHEMBL5401557 | 0.79 | KDM4E (0.44) | CHEK1ALDH1A1KMT2APOLBRAB9A | |
| SCHEMBL6088155 | 0.78 | CYP3A4 (0.38) | CHEK1ALDH1A1KMT2APOLBKDM4E | |
| SCHEMBL1981272 | 0.76 | KDR (0.51) | CHEK1FGFR1KDRPDGFRBAURKA | |
| SCHEMBL10810611 | 0.74 | ALDH1A1 (0.34) | ALDH1A1KMT2APOLBRAB9A | |
| SCHEMBL29956467 | 0.73 | ALDH1A1 (0.34) | ALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |