SCHEMBL5358334

SCHEMBL5358334

CCc1c(C)[nH]c(C=O)c1C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
HSD17B10 Q99714 3/20 0.39
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39
KMT2A Q03164 2/20 0.36
POLB P06746 1/20 0.36
IGF1R P08069 1/20 0.36
PDGFRB P09619 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
HTT P42858 1/20 0.34
MAPT P10636 1/20 0.34
STAT1 P42224 1/20 0.34
RAB9A P51151 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.33
BRD4 O60885 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29954782 0.84 ALDH1A1 (0.37) ALDH1A1HSD17B10KMT2APOLBIGF1R
SCHEMBL14543745 0.83 PDGFRB (0.44) ALDH1A1HSD17B10KDM4EHPGDALOX15
SCHEMBL15380984 0.83 ALDH1A1 (0.36) ALDH1A1HSD17B10KMT2APOLBIGF1R
SCHEMBL16212888 0.81 PDGFRB (0.34) ALDH1A1HSD17B10KMT2APDGFRBHTT
SCHEMBL28147350 0.81 ALDH1A1 (0.32) ALDH1A1KMT2APOLBCHEK1
SCHEMBL29951966 0.81 CHEK1 (0.37) ALDH1A1KDM4EKMT2APOLBPDGFRB
SCHEMBL6088532 0.81 CHEK1 (0.34) ALDH1A1KMT2APOLBCHEK1
SCHEMBL6088155 0.79 CYP3A4 (0.38) ALDH1A1HSD17B10KDM4EHPGDKMT2A
SCHEMBL13228907 0.79 ALDH1A1 (0.34) ALDH1A1HSD17B10KMT2APOLBIGF1R
SCHEMBL6089467 0.79 KDM4E (0.37) ALDH1A1HSD17B10KDM4EHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117603385-A Preparation method and application of green fluorescent microspheres 苏州纳微生命科技有限公司 2024-02-27 CN claimed
US-20250089549-A1 OPTICAL FILM, COMPOSITION FOR FORMING COLORED LAYER, DIPYRROMETHENE COBALT COMPLEX AND DISPLAY DEVICE TOPPAN HOLDINGS INC. (JP) 2025-03-13 US disclosed
EP-4462164-A1 OPTICAL FILM, COMPOSITION FOR COLORED LAYER FORMATION, DIPYRROMETHENE COBALT COMPLEX, AND DISPLAY DEVICE Toppan Holdings Inc. (JP) 2024-11-13 EP disclosed
CN-118511098-A Optical film, composition for forming colored layer, dipyrromethene cobalt complex, and display device 凸版控股株式会社 2024-08-16 CN disclosed
CN-117603385-A Preparation method and application of green fluorescent microspheres 苏州纳微生命科技有限公司 2024-02-27 CN disclosed
WO-2023233864-A1 OPTICAL FILM, COMPOSITION FOR COLORED LAYER FORMATION, DIPYRROMETHENE COBALT COMPLEX, AND DISPLAY DEVICE 凸版印刷株式会社 2023-12-07 WO disclosed
CN-113816989-B Suspension pyrrolyl amino-indenyl titanium dichloride compound and application thereof in olefin high-temperature polymerization 惠生(中国)投资有限公司 2023-09-19 CN disclosed
WO-2023132318-A1 OPTICAL FILM, COMPOSITION FOR COLORED LAYER FORMATION, DIPYRROMETHENE COBALT COMPLEX, AND DISPLAY DEVICE 凸版印刷株式会社 2023-07-13 WO disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-20220031870-A1 METAL COMPLEXES AND FLUORINATION THEREOF UNIVERSITY OF SOUTHAMPTON (GB) 2022-02-03 US disclosed
EP-2991969-A1 METAL COMPLEXES AND FLUORINATION THEREOF GE Healthcare UK Limited (GB) 2016-03-09 EP disclosed
CN-105339013-A Metal complexes and fluorination thereof GE HEALTHCARE LTD 2016-02-17 CN disclosed
CN-105324367-A Metal complexes and fluorination thereof GE HEALTHCARE LTD 2016-02-10 CN disclosed
WO-2014177689-A1 METAL COMPLEXES AND FLUORINATION THEREOF GE HEALTHCARE LIMITED (GB) 2014-11-06 WO disclosed
WO-2014177690-A1 METAL COMPLEXES AND THEIR FLUORINATION GE HEALTHCARE LIMITED (GB) 2014-11-06 WO disclosed
CN-102124076-A Fluorescent compounds for the diagnosis of infections, production method, and applications thereof CONSEJO SUPERIOR INVESTIGACION 2011-07-13 CN disclosed
US-7202265-B2 Indolinone combinatorial libraries and related products and methods for the treatment of disease SUGEN, INC. (US) 2007-04-10 US disclosed
US-20050197382-A1 Indolinone combinatorial libraries and related products and methods for the treatment of disease SUGEN, INC. 2005-09-08 US disclosed
US-6506763-B2 Useful in prevention and treatment of protein kinase related disorders such as cancer SUGEN, INC. 2003-01-14 US disclosed
US-6133305-A PREVENTION AND TREATMENT OF PROTEIN KINASE RELATED DISORDERS SUCH AS CANCER SUGEN, INC. (US) 2000-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220031870-A1 METAL COMPLEXES AND FLUORINATION THEREOF FOS, FGB, FOSB ALDH1A1 3176/4885HSD17B10 1930/4885KDM4E 3099/4885
US-20050197382-A1 Indolinone combinatorial libraries and related products and methods for the treatment of disease FRK, PTK2, DSTYK ALDH1A1 2044/4885HSD17B10 1762/4885KDM4E 2527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.