Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.62 |
| ▸ | CA1 | P00915 | 6/20 | 0.62 |
| ▸ | CA2 | P00918 | 6/20 | 0.62 |
| ▸ | CA7 | P43166 | 6/20 | 0.62 |
| ▸ | CA9 | Q16790 | 6/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2825641 | 1.00 | CA12 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9108508 | 0.86 | CA12 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9110483 | 0.85 | CA1 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15516681 | 0.82 | CA2 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29712893 | 0.81 | MEN1 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18593627 | 0.81 | TTBK1 (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL660617 | 0.81 | MEN1 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29597336 | 0.81 | ALDH1A1 (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL237491 | 0.81 | ALDH1A1 (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17464347 | 0.81 | KDM4E (0.46) | CA1CA2LMNATSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |