Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 2/20 | 0.46 |
| ▸ | TTK | P33981 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951522 | 0.84 | MAP4K4 (0.51) | CHEK2FYNMKNK1AXLMAP4K4 | |
| SCHEMBL29951774 | 0.83 | CHEK2 (0.51) | CHEK2FYNMKNK1CYP2A6CYP1A2 | |
| SCHEMBL2558901 | 0.78 | CHEK2 (0.53) | CHEK2FYNMKNK1MAP4K4 | |
| SCHEMBL26916929 | 0.76 | CHEK2 (0.55) | CHEK2FYNTDO2HSP90AA1HSP90AB1 | |
| SCHEMBL29582616 | 0.76 | CHEK2 (0.55) | CHEK2FYNTDO2HSP90AA1HSP90AB1 | |
| SCHEMBL2561948 | 0.75 | MAP4K4 (0.54) | CHEK2FYNTDO2MKNK1MEN1 | |
| SCHEMBL3931286 | 0.75 | TTK (0.49) | LOXL2ERN1TTKMKNK1MKNK2 | |
| SCHEMBL21994688 | 0.74 | PDGFRB (0.61) | CHEK2FYNMKNK1MKNK2CYP11B1 | |
| SCHEMBL29994102 | 0.74 | PDGFRB (0.61) | CHEK2FYNMKNK1MKNK2CYP11B1 | |
| SCHEMBL2559978 | 0.74 | ADORA2A (0.49) | CYP3A4CYP2C9CYP2C19CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |