Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 6/20 | 0.51 |
| ▸ | USP7 | Q93009 | 3/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.44 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951774 | 0.85 | CHEK2 (0.51) | MAP4K4USP7CHEK2MKNK1FYN | |
| SCHEMBL29952012 | 0.84 | CHEK2 (0.54) | MAP4K4CHEK2MKNK1FYNAXL | |
| SCHEMBL2561948 | 0.83 | MAP4K4 (0.54) | MAP4K4USP7CHEK2MKNK1FYN | |
| SCHEMBL2558901 | 0.83 | CHEK2 (0.53) | MAP4K4USP7CHEK2MKNK1FYN | |
| SCHEMBL2557950 | 0.80 | MAP4K4 (0.56) | MAP4K4USP7CHEK2PDGFRBKDR | |
| SCHEMBL2559978 | 0.79 | ADORA2A (0.49) | MAP4K4PDGFRBKDR | |
| SCHEMBL8550043 | 0.79 | ALDH1A1 (0.39) | MAP4K4AXL | |
| SCHEMBL2554196 | 0.79 | USP7 (0.41) | MAP4K4USP7 | |
| SCHEMBL2554637 | 0.76 | ADORA1 (0.46) | MAP4K4CHEK2FYN | |
| SCHEMBL2554311 | 0.76 | MAP4K4 (0.43) | MAP4K4CHEK2FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |