Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.77 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.77 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7822572 | 0.86 | ALDH1A1 (0.71) | PARP1PARP10APEX1ALDH1A1TDP1 | |
| SCHEMBL15331088 | 0.83 | SMN1; SMN2 (0.55) | PARP1PARP10ALDH1A1MEN1KMT2A | |
| SCHEMBL15866806 | 0.80 | ALDH1A1 (0.53) | PARP1PARP10APEX1ALDH1A1MEN1 | |
| SCHEMBL5816312 | 0.78 | ALDH1A1 (0.85) | ALDH1A1MEN1KMT2ALMNATDP1 | |
| SCHEMBL15709837 | 0.78 | ALDH1A1 (0.83) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL15866803 | 0.78 | ALDH1A1 (0.54) | PARP1PARP10APEX1ALDH1A1MEN1 | |
| SCHEMBL20559746 | 0.77 | PARP1 (0.61) | PARP1PARP10ALDH1A1MEN1KMT2A | |
| SCHEMBL20559230 | 0.77 | PARP1 (0.61) | PARP1PARP10ALDH1A1MEN1KMT2A | |
| SCHEMBL13927086 | 0.77 | PARP1 (0.61) | PARP1PARP10APEX1ALDH1A1MEN1 | |
| SCHEMBL13927083 | 0.77 | PARP1 (0.61) | PARP1PARP10APEX1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |