Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | PARP1 | P09874 | 1/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.57 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952075 | 0.86 | PARP1 (0.77) | ALDH1A1SMN1; SMN2TDP1HTTPARP1 | |
| SCHEMBL8352882 | 0.82 | ALDH1A1 (0.71) | ALDH1A1TDP1 | |
| SCHEMBL7829665 | 0.78 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2TDP1POLBHTT | |
| SCHEMBL7832978 | 0.77 | GAA (0.70) | ALDH1A1SMN1; SMN2TDP1POLBHTT | |
| SCHEMBL5816312 | 0.76 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2TDP1HTT | |
| SCHEMBL7831950 | 0.74 | KMT2A (0.72) | ALDH1A1SMN1; SMN2TDP1POLBHTT | |
| SCHEMBL3926210 | 0.74 | POLB (0.82) | ALDH1A1SMN1; SMN2TDP1POLBHTT | |
| SCHEMBL9532585 | 0.74 | ALDH1A1 (0.91) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL4102809 | 0.73 | KMT2A (0.73) | ALDH1A1SMN1; SMN2TDP1POLB | |
| SCHEMBL15866803 | 0.73 | ALDH1A1 (0.54) | ALDH1A1TDP1PARP1PARP10APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |