Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.38 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29393116 | 0.88 | AAK1 (0.46) | CYP17A1RXFP1BRAFKCNQ4KCNQ5 | |
| SCHEMBL29071979 | 0.88 | AAK1 (0.46) | CYP17A1RXFP1BRAFKCNQ4KCNQ5 | |
| SCHEMBL25037252 | 0.85 | CYP17A1 (0.39) | CYP17A1RXFP1BRAFKCNQ4KCNQ5 | |
| SCHEMBL29954656 | 0.85 | KCNQ4 (0.46) | CYP17A1RXFP1KCNQ4KCNQ5CA12 | |
| SCHEMBL29951652 | 0.84 | KCNQ4 (0.43) | CYP17A1RXFP1BRAFKCNQ4KCNQ5 | |
| SCHEMBL14725520 | 0.83 | CYP17A1 (0.48) | CYP17A1RXFP1BRAFKCNQ4KCNQ5 | |
| SCHEMBL29954103 | 0.82 | ALDH1A1 (0.46) | POLBAAK1ATRERN1 | |
| SCHEMBL26405293 | 0.81 | CYP17A1 (0.41) | CYP17A1RXFP1BRAFKCNQ4KCNQ5 | |
| SCHEMBL22482353 | 0.81 | CYP17A1 (0.43) | CYP17A1RXFP1BRAFKCNQ4KCNQ5 | |
| SCHEMBL29675242 | 0.81 | CYP17A1 (0.43) | CYP17A1RXFP1BRAFKCNQ4KCNQ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514789-A1 | <SUP2/>? <SUB2/>?V?BICYCLIC HETEROCYCLIC AMIDE INHIBITORS OF NA1.8 FOR THE TREATMENT OF PAIN | SiteOne Therapeutics, Inc. (US) | 2025-03-05 | — | — | EP | disclosed |
| WO-2023211990-A1 | BICYCLIC HETEROCYCLIC AMIDE INHIBITORS OF NA V1.8 FOR THE TREATMENT OF PAIN | SITEONE THERAPEUTICS, INC. (US) | 2023-11-02 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |