Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ4 | P56696 | 3/20 | 0.46 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951652 | 0.90 | KCNQ4 (0.43) | KCNQ4KCNQ5CYP17A1RXFP1CA12 | |
| SCHEMBL3292146 | 0.87 | HPGD (0.46) | KCNQ4KCNQ5CYP17A1RXFP1GAA | |
| SCHEMBL29956441 | 0.87 | HPGD (0.46) | KCNQ4KCNQ5CYP17A1RXFP1GAA | |
| SCHEMBL5425869 | 0.85 | CA12 (0.49) | CYP17A1RXFP1GAACA12CA1 | |
| SCHEMBL29956545 | 0.85 | MIF (0.43) | KCNQ4KCNQ5CYP17A1RXFP1GAA | |
| SCHEMBL29952152 | 0.85 | CYP17A1 (0.42) | KCNQ4KCNQ5CYP17A1RXFP1CA12 | |
| SCHEMBL29950895 | 0.85 | RXFP1 (0.51) | KCNQ4KCNQ5CYP17A1RXFP1HTT | |
| SCHEMBL6755112 | 0.85 | RXFP1 (0.51) | KCNQ4KCNQ5CYP17A1RXFP1HTT | |
| SCHEMBL8140376 | 0.84 | NPC1 (0.45) | CYP17A1POLB | |
| SCHEMBL16802013 | 0.84 | HSP90AA1 (0.43) | CYP17A1RXFP1GAACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |