SCHEMBL2995216

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3724914	0.96	KIT (0.48)	KITVCPBRD4ALDH1A1KMT2A
	SCHEMBL3723439	0.95	KIT (0.49)	KITVCPBRD4ALDH1A1KMT2A
	SCHEMBL27237619	0.87	KIT (0.48)	KITVCPBRD4ALDH1A1NPC1
	SCHEMBL3000216	0.86	NPY5R (0.50)	BRD4MAPTMAPK1PIM1PIM2
	SCHEMBL27808315	0.84	EPHX2 (0.44)	VCPMAPT
	SCHEMBL2999826	0.84	VCP (0.40)	VCPBRD4SYK
	SCHEMBL30849060	0.83	KIT (0.45)	KITVCPBRD4ALDH1A1KMT2A
	SCHEMBL27237585	0.83	KIT (0.45)	KITVCPBRD4ALDH1A1KMT2A
	SCHEMBL3003738	0.81	VCP (0.44)	VCPBRD4
	SCHEMBL3724911	0.80	KIT (0.38)	KITVCPBRD4HPGDSUSP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.