Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 2/20 | 0.34 |
| ▸ | G6PD | P11413 | 2/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5925147 | 1.00 | S100A4 (0.58) | S100A4TDP1MEN1NPC1RAB9A | |
| SCHEMBL5925156 | 0.84 | S100A4 (0.41) | S100A4TDP1MEN1NPC1RAB9A | |
| SCHEMBL6295329 | 0.83 | S100A4 (0.40) | S100A4TDP1NPC1RAB9ATDP2 | |
| SCHEMBL6294367 | 0.82 | S100A4 (0.62) | S100A4TDP1MEN1NPC1RAB9A | |
| SCHEMBL21801779 | 0.81 | S100A4 (0.60) | S100A4TDP1MEN1NPC1RAB9A | |
| SCHEMBL5925219 | 0.74 | APAF1 (0.48) | S100A4TDP2G6PDHKDC1NSD2 | |
| SCHEMBL21801897 | 0.74 | S100A4 (0.56) | S100A4TDP1MEN1NPC1RAB9A | |
| SCHEMBL21801718 | 0.74 | S100A4 (0.58) | S100A4TDP1MEN1NPC1RAB9A | |
| SCHEMBL2599397 | 0.73 | S100A4 (1.00) | S100A4TDP1MEN1NPC1RAB9A | |
| SCHEMBL21801712 | 0.73 | S100A4 (0.57) | S100A4TDP1MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |