SCHEMBL29952248

SCHEMBL29952248

c1cc2c3c(ccc2[nH]1)CCCO3

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.40
DRD4 P21917 1/20 0.40
DRD3 P35462 1/20 0.40
HTR1D P28221 11/20 0.38
HTR1B P28222 7/20 0.37
HTR1A P08908 3/20 0.33
SLC6A4 P31645 3/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
MAPK1 P28482 1/20 0.32
AHR P35869 1/20 0.32
PARP1 P09874 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19118540 0.73 IDO1 (0.40) HTR2AHTR2CHTR2B
SCHEMBL3900178 0.73 ADRA2A (0.39) DRD2DRD4DRD3HTR1ASLC6A4
SCHEMBL6092206 0.72 HTR1D (0.47) DRD2HTR1DHTR1BHTR1AHTR2A
SCHEMBL25521233 0.71 HTR1D (0.53) HTR1DHTR1BPARP1
SCHEMBL31727562 0.71 HTR1D (0.53) HTR1DHTR1BPARP1
SCHEMBL7449710 0.71 HTR1D (0.53) DRD2DRD4DRD3HTR1DHTR1B
SCHEMBL29910203 0.68 NFKB1 (0.40)
SCHEMBL1971305 0.68 NFKB1 (0.40)
SCHEMBL1536403 0.68 DAO (0.40) PARP1
SCHEMBL11437391 0.67 AHR (0.39) DRD2DRD4DRD3HTR1DHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702652-B2 Enzymatic encoding methods for efficient synthesis of large libraries NUEVOLUTION A/S (DK) 2023-07-18 US disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed