Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.86 |
| ▸ | MAOB | P27338 | 5/20 | 0.74 |
| ▸ | MAOA | P21397 | 4/20 | 0.74 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5363245 | 0.93 | PTPN1 (1.00) | PTPN1MAOBMAOAPTPN2ALDH1A1 | |
| SCHEMBL29952282 | 0.86 | PTPN1 (1.00) | PTPN1MAOBMAOAPTPN2ALDH1A1 | |
| SCHEMBL127924 | 0.86 | PTPN1 (1.00) | PTPN1MAOBMAOAPTPN2ALDH1A1 | |
| SCHEMBL29958044 | 0.83 | PTPN1 (0.77) | PTPN1MAOBMAOAPTPN2ALDH1A1 | |
| SCHEMBL15898959 | 0.81 | PTPN1 (0.78) | PTPN1MAOBMAOAPTPN2ALDH1A1 | |
| SCHEMBL29954035 | 0.77 | PTPN1 (1.00) | PTPN1MAOBMAOAPTPN2ALDH1A1 | |
| SCHEMBL4696452 | 0.75 | AHR (0.61) | MAOAALDH1A1POLB | |
| SCHEMBL28874629 | 0.75 | MAOB (0.71) | PTPN1MAOBMAOAALDH1A1 | |
| SCHEMBL11594586 | 0.75 | MAOA (0.67) | MAOAALDH1A1POLB | |
| SCHEMBL218740 | 0.75 | MAOA (0.67) | MAOAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028366-A9 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | DURECT CORP (US) | 2003-02-13 | — | — | WO | disclosed |