Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 3/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306345 | 1.00 | TSHR (0.52) | TSHRHSD17B10ALDH1A1CYP3A4TDP1 | |
| SCHEMBL24165 | 0.81 | TTR (0.57) | TSHRHSD17B10ALDH1A1TTRENPP2 | |
| SCHEMBL130450 | 0.80 | TTR (0.61) | TSHRHSD17B10CYP3A4TTRENPP2 | |
| SCHEMBL1277359 | 0.77 | ENPP2 (0.50) | TSHRALDH1A1TTRENPP2CA1 | |
| SCHEMBL24730423 | 0.74 | TTR (0.50) | TSHRALDH1A1TTRENPP2CA1 | |
| SCHEMBL177405 | 0.74 | TTR (0.50) | TTRENPP2CA1CA2 | |
| SCHEMBL29427126 | 0.74 | TTR (0.50) | TTRENPP2CA1CA2 | |
| SCHEMBL1529238 | 0.74 | CA1 (0.52) | TSHRALDH1A1TTRENPP2CA1 | |
| SCHEMBL310780 | 0.74 | TTR (0.50) | TSHRTTRENPP2CA1CA2 | |
| SCHEMBL29465759 | 0.74 | TTR (0.50) | TSHRTTRENPP2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |