SCHEMBL1277359

SCHEMBL1277359

OB(O)c1ccc(O)c(O)c1

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 5/20 0.50
CA2 P00918 3/20 0.46
CA1 P00915 2/20 0.46
APP P05067 1/20 0.46
TSHR P16473 1/20 0.42
LPL P06858 1/20 0.42
LIPG Q9Y5X9 1/20 0.42
TRPA1 O75762 1/20 0.42
TTR P02766 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LCK P06239 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16426121 0.79 ENPP2 (0.46) ENPP2CA2CA1TSHRLPL
SCHEMBL2010727 0.77 TP53 (0.52) ENPP2CA2CA1LPLLIPG
SCHEMBL423468 0.77 ENPP2 (0.44) ENPP2CA2CA1TSHRTTR
SCHEMBL24165 0.77 TTR (0.57) ENPP2CA2CA1TSHRTTR
SCHEMBL309397 0.77 CA3 (0.52) ENPP2CA2CA1TTR
SCHEMBL306345 0.77 TSHR (0.52) ENPP2CA2CA1TSHRTTR
SCHEMBL3791258 0.77 ALOX15 (0.52) ENPP2CA2CA1TSHRLPL
SCHEMBL16654491 0.77 CA2 (0.48) ENPP2CA2CA1TSHRLPL
SCHEMBL792416 0.77 TSHR (0.48) ENPP2CA2CA1TSHRLPL
SCHEMBL29952333 0.77 TSHR (0.52) ENPP2CA2CA1TSHRTTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120904648-A Polylactic acid color master batch and preparation method thereof 丙烽(安徽)科技有限公司 2025-11-07 CN disclosed
WO-2025053379-A1 NOVEL COMPOUND AND USE THEREOF FOR TREATING PSORIASIS 광주과학기술원 2025-03-13 WO disclosed
WO-2025037870-A1 BENZOFURAN COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME FOR PREVENTING OR TREATING CANCER DISEASES AND CANCER METASTASIS 한국생명공학연구원 2025-02-20 WO disclosed
EP-3199558-B1 COMPOUND HAVING FOUR POLYMERIZABLE GROUPS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2019-10-30 EP disclosed
EP-2842974-B1 COMPOUND HAVING FOUR POLYMERIZABLE GROUPS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2019-03-13 EP disclosed
EP-3199558-A1 COMPOUND HAVING FOUR POLYMERIZABLE GROUPS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC Corporation (JP) 2017-08-02 EP disclosed
EP-3168219-A1 PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYL METHYL GROUP DAIICHI SANKYO COMPANY, LIMITED (JP) 2017-05-17 EP disclosed
US-9617477-B2 Compound having four polymerizable groups, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2017-04-11 US disclosed
US-9617477-B2 Compound having four polymerizable groups, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2017-04-11 US disclosed
US-9617477-B2 Compound having four polymerizable groups, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2017-04-11 US disclosed
EP-2473504-B1 HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK BIOENERGENIX (US) 2015-02-25 EP disclosed
US-20130277609-A1 COMPOUND HAVING FOUR POLYMERIZABLE GROUPS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-10-24 US disclosed
US-20130277609-A1 COMPOUND HAVING FOUR POLYMERIZABLE GROUPS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-10-24 US disclosed
US-20130277609-A1 COMPOUND HAVING FOUR POLYMERIZABLE GROUPS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-10-24 US disclosed
US-20120088737-A2 NOVEL ACYL GUANIDINE DERIVATIVES AJINOMOTO CO., INC (JP) 2012-04-12 US disclosed
WO-2012001107-A1 PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-01-05 WO disclosed
US-20110082109-A1 NOVEL ACYL GUANIDINE DERIVATIVES AJINOMOTO CO., INC. (JP) 2011-04-07 US disclosed
WO-2011028947-A2 HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK BIOENERGENIX (US) 2011-03-10 WO disclosed
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110082109-A1 NOVEL ACYL GUANIDINE DERIVATIVES SLC9A3, NHERF1, SLC9A2 ENPP2 842/4885CA2 516/4885CA1 3641/4885
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND NISCH, BLVRB, BBOX1 ENPP2 1920/4885CA2 1992/4885CA1 3273/4885
US-20120088737-A2 NOVEL ACYL GUANIDINE DERIVATIVES SLC9A3, NHERF1, SLC9A2 ENPP2 842/4885CA2 516/4885CA1 3641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.