Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29363233 | 0.82 | KDM4E (0.45) | HPGDAHRMEN1MAPTKMT2A | |
| SCHEMBL10493559 | 0.82 | KDM4E (0.45) | HPGDAHRMEN1MAPTKMT2A | |
| SCHEMBL29951382 | 0.80 | HPGD (0.43) | HPGDCHRNB2CHRNA7CHRNA4KIF11 | |
| SCHEMBL29956720 | 0.78 | KIF11 (0.50) | HPGDMEN1KMT2AKIF11 | |
| SCHEMBL29951788 | 0.77 | HPGD (0.44) | HPGDCHRNB2CHRNA7CHRNA4MAPT | |
| SCHEMBL29951414 | 0.77 | MEN1 (0.44) | HPGDMEN1KMT2AKIF11GAA | |
| SCHEMBL14519076 | 0.77 | GSK3B (0.53) | HPGDAHRMEN1MAPTKMT2A | |
| SCHEMBL31377086 | 0.76 | HPGD (0.56) | HPGDCHRNB2CHRNA7CHRNA4AHR | |
| SCHEMBL248974 | 0.76 | HPGD (0.61) | HPGDAHRMEN1MAPTKMT2A | |
| SCHEMBL29378092 | 0.76 | HPGD (0.61) | HPGDAHRMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |