Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3559655 | 0.81 | MEN1 (0.60) | GBA1NAMPTGAAMEN1KMT2A | |
| SCHEMBL20389106 | 0.80 | MEN1 (0.55) | GBA1NAMPTGAAMEN1KMT2A | |
| SCHEMBL3914463 | 0.78 | NAMPT (0.63) | GBA1NAMPTGAAMEN1KMT2A | |
| SCHEMBL20379964 | 0.75 | MAPT (0.63) | GBA1GAAMEN1KMT2ARAB9A | |
| SCHEMBL29611829 | 0.74 | PTPN1 (0.58) | GBA1NAMPTGAAMEN1KMT2A | |
| SCHEMBL387376 | 0.73 | TRPV1 (0.81) | TRPV1MEN1KMT2ARAB9AHTT | |
| SCHEMBL18825696 | 0.72 | NAMPT (0.50) | GBA1NAMPTGAAMEN1KMT2A | |
| SCHEMBL2557984 | 0.72 | RAB9A (0.68) | MEN1KMT2AHSD17B10RAB9ALMNA | |
| SCHEMBL6328024 | 0.72 | GBA1 (0.57) | GBA1NAMPTGAAMEN1KMT2A | |
| SCHEMBL14394393 | 0.72 | NPC1 (0.69) | MEN1KMT2ARAB9AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |