Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 2/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.32 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5751655 | 1.00 | POLB (0.36) | POLBTDP1NNMTENPP2TXNRD1 | |
| SCHEMBL22281202 | 0.89 | POLB (0.34) | POLBTDP1NNMTTXNRD1SIRT2 | |
| SCHEMBL16294781 | 0.77 | POLB (0.38) | POLBTDP1NNMTENPP2TXNRD1 | |
| SCHEMBL19364178 | 0.77 | POLB (0.38) | POLBTDP1NNMTTXNRD1KDM4E | |
| SCHEMBL29956451 | 0.77 | POLB (0.38) | POLBTDP1NNMTENPP2TXNRD1 | |
| SCHEMBL29653296 | 0.75 | NNMT (0.50) | POLBTDP1NNMTENPP2ALDH1A1 | |
| SCHEMBL248283 | 0.75 | NNMT (0.50) | POLBTDP1NNMTENPP2ALDH1A1 | |
| SCHEMBL17586768 | 0.75 | TXNRD1 (0.36) | POLBTDP1NNMTTXNRD1SIRT2 | |
| SCHEMBL15077682 | 0.75 | KMT2A (0.42) | POLBTDP1NNMTTXNRD1ALDH1A1 | |
| SCHEMBL321488 | 0.75 | POLB (0.52) | POLBTDP1NNMTENPP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |