Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958267 | 0.90 | CREBBP (0.54) | CREBBPHTTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL29951914 | 0.87 | HPGD (0.61) | ALDH1A1KMT2AL3MBTL1MEN1HPGD | |
| SCHEMBL3200442 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KMT2AL3MBTL1MEN1CYP2D6 | |
| SCHEMBL29951085 | 0.80 | HPGD (0.58) | ALDH1A1KMT2AL3MBTL1MEN1HPGD | |
| SCHEMBL29953750 | 0.77 | CREBBP (0.55) | CREBBPHTTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL23121294 | 0.76 | HIF1A (0.58) | ALDH1A1KMT2AMEN1HPGDKDM4E | |
| SCHEMBL14667296 | 0.76 | CREBBP (0.64) | CREBBPHTTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL29951426 | 0.76 | HPGD (0.60) | ALDH1A1KMT2AL3MBTL1MEN1HPGD | |
| SCHEMBL5119766 | 0.75 | CREBBP (0.62) | CREBBPHTTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL29952856 | 0.74 | CREBBP (0.54) | CREBBPHTTALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |