Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955849 | 0.87 | ALDH1A1 (0.55) | HTTALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL29958267 | 0.79 | CREBBP (0.54) | CREBBPHTTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL29952391 | 0.77 | CREBBP (0.51) | CREBBPHTTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL14667296 | 0.76 | CREBBP (0.64) | CREBBPHTTALDH1A1HIF1AKMT2A | |
| SCHEMBL5119766 | 0.75 | CREBBP (0.62) | CREBBPHTTALDH1A1HIF1AKMT2A | |
| SCHEMBL3034164 | 0.72 | CREBBP (0.72) | CREBBPHTTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL29463757 | 0.72 | CREBBP (0.72) | CREBBPHTTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL27967180 | 0.71 | CREBBP (0.57) | CREBBPHTTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL17395801 | 0.71 | CREBBP (1.00) | CREBBPHTTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL29952856 | 0.71 | CREBBP (0.54) | CREBBPHTTALDH1A1HIF1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |