Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.52 |
| ▸ | ALDH5A1 | P51649 | 3/20 | 0.47 |
| ▸ | ABAT | P80404 | 3/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | IAPP | P10997 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11856373 | 1.00 | KDM4E (0.57) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL19923143 | 0.84 | KDM4E (0.57) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL6515392 | 0.83 | KDM4E (0.61) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL3406735 | 0.81 | ALDH1A1 (0.52) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL1575198 | 0.78 | ALDH1A1 (0.48) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL1575377 | 0.76 | ALDH1A1 (0.57) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL7951906 | 0.76 | ALDH1A1 (0.47) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL5760222 | 0.76 | ALDH1A3 (0.47) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL1576019 | 0.76 | ALDH1A1 (0.47) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| Protocatechualdehyde SCHEMBL29196221 | 0.74 | KDM4E (0.91) | KDM4EPTGS2RAB9AALDH1A1AOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |