Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL262197 | 1.00 | KDM4E (0.59) | KDM4EATML3MBTL1ENPP2CA4 | |
| SCHEMBL29375327 | 1.00 | KDM4E (0.59) | KDM4EATML3MBTL1ENPP2CA4 | |
| SCHEMBL12014934 | 0.94 | CA1 (0.53) | KDM4EATML3MBTL1ENPP2CA4 | |
| SCHEMBL16689548 | 0.91 | KDM4E (0.50) | KDM4EATML3MBTL1ENPP2CA4 | |
| SCHEMBL17885353 | 0.91 | KDM4E (0.50) | KDM4EATML3MBTL1ENPP2CA4 | |
| SCHEMBL28640199 | 0.90 | KDM4E (0.48) | KDM4EATML3MBTL1ENPP2CA4 | |
| SCHEMBL28595803 | 0.90 | KDM4E (0.58) | KDM4EATML3MBTL1ENPP2CA4 | |
| SCHEMBL30471732 | 0.90 | KDM4E (0.58) | KDM4EATML3MBTL1ENPP2CA4 | |
| SCHEMBL18525478 | 0.89 | KDM4E (0.52) | KDM4EATML3MBTL1ENPP2CA4 | |
| SCHEMBL17753312 | 0.87 | L3MBTL1 (0.46) | KDM4EATML3MBTL1ENPP2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |