Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17885353 | 0.98 | KDM4E (0.50) | KDM4EL3MBTL1ATMCA1CA2 | |
| SCHEMBL29943786 | 0.95 | KDM4E (0.60) | KDM4EL3MBTL1ATMCA1CA2 | |
| SCHEMBL29407532 | 0.95 | KDM4E (0.60) | KDM4EL3MBTL1ATMCA1CA2 | |
| SCHEMBL260470 | 0.95 | KDM4E (0.60) | KDM4EL3MBTL1ATMCA1CA2 | |
| SCHEMBL15762939 | 0.94 | KDM4E (0.55) | KDM4EL3MBTL1ATMCA1CA2 | |
| SCHEMBL18526037 | 0.94 | KDM4E (0.55) | KDM4EL3MBTL1ATMCA1CA2 | |
| SCHEMBL355186 | 0.92 | KDM4E (0.44) | KDM4EL3MBTL1ATMCA1CA2 | |
| SCHEMBL29975845 | 0.92 | MGLL (0.49) | KDM4EL3MBTL1ATMCA1CA2 | |
| SCHEMBL31050121 | 0.92 | KDM4E (0.44) | KDM4EL3MBTL1ATMCA1CA2 | |
| SCHEMBL30296694 | 0.92 | KDM4E (0.44) | KDM4EL3MBTL1ATMCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10934292-B2 | Hexamethylindanes | MERCK PATENT GMBH (DE) | 2021-03-02 | — | — | US | disclosed |
| EP-3334708-B1 | HEXAMETHYLINDANES | MERCK PATENT GMBH (DE) | 2020-08-19 | — | — | EP | disclosed |
| US-20200140440-A1 | HEXAMETHYLINDANES | MERCK PATENT GMBH (DE) | 2020-05-07 | — | — | US | disclosed |
| US-20180141957-A1 | COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF | DUK SAN NEOLUX CO., LTD. (KR) | 2018-05-24 | — | — | US | disclosed |
| WO-2017025166-A1 | HEXAMETHYLINDANES | MERCK PATENT GMBH (DE) | 2017-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10934292-B2 | Hexamethylindanes | ALKBH5, ALKBH2, METTL3 | KDM4E 431/4885L3MBTL1 997/4885ATM 4525/4885 |
| US-20180141957-A1 | COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF | PIEZO1, OCIAD1, LEF1 | KDM4E 1121/4885L3MBTL1 561/4885ATM 4361/4885 |
| US-20200140440-A1 | HEXAMETHYLINDANES | ALKBH5, ALKBH2, METTL3 | KDM4E 431/4885L3MBTL1 997/4885ATM 4525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.