Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561954 | 0.89 | KDM4E (0.47) | POLBALDH1A1NPC1MAPTHPGD | |
| SCHEMBL15332743 | 0.85 | PKM (0.49) | POLBALDH1A1NPC1HPGDTSHR | |
| SCHEMBL12376672 | 0.83 | HPGD (0.59) | POLBALDH1A1NPC1MAPTLMNA | |
| SCHEMBL2561844 | 0.83 | TSHR (0.53) | POLBALDH1A1NPC1LMNAHPGD | |
| SCHEMBL2563246 | 0.82 | SMN1; SMN2 (0.56) | POLBALDH1A1NPC1MAPTLMNA | |
| SCHEMBL15330690 | 0.81 | TSHR (0.54) | ALDH1A1MAPTLMNAHPGDTSHR | |
| SCHEMBL2562343 | 0.81 | HPGD (0.48) | POLBALDH1A1NPC1LMNAHPGD | |
| SCHEMBL2558834 | 0.80 | SMN1; SMN2 (0.51) | POLBALDH1A1NPC1MAPTCASP3 | |
| SCHEMBL2554392 | 0.80 | RAB9A (0.53) | POLBALDH1A1NPC1LMNAHPGD | |
| SCHEMBL2559435 | 0.80 | MEN1 (0.49) | POLBALDH1A1NPC1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |