SCHEMBL2995247

SCHEMBL2995247

C=C(C)COCOCOP(=O)(O)OP(=O)(O)O

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BTN3A1 O00481 3/20 0.54
MVD P53602 3/20 0.37
FNTA P49354 7/20 0.36
FNTB P49356 5/20 0.36
PGGT1B P53609 5/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2999012 0.93 BTN3A1 (0.44) BTN3A1
SCHEMBL3000757 0.91 BTN3A1 (0.43) BTN3A1
SCHEMBL3000758 0.91 BTN3A1 (0.45) BTN3A1MVDFNTAFNTBPGGT1B
SCHEMBL22235266 0.81 BTN3A1 (0.66) BTN3A1MVDFNTAFNTBPGGT1B
SCHEMBL19472455 0.76 BTN3A1 (0.36) BTN3A1
SCHEMBL6462210 0.75 BTN3A1 (0.35) BTN3A1
SCHEMBL8757061 0.75 TSHR (0.35) BTN3A1
SCHEMBL12306868 0.74 BTN3A1 (0.47) BTN3A1MVDFNTAFNTBPGGT1B
SCHEMBL3062980 0.72 BTN3A1 (0.52) BTN3A1MVDFNTAFNTBPGGT1B
SCHEMBL2455670 0.72 BTN3A1 (0.32) BTN3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100254940-A1 Compositions and Methods for Regulating an Immune Response in a Subject INNATE PHARMA, S.A. (FR) 2010-10-07 US disclosed
US-20100189681-A1 Methods of Using Phosphoantigens Together with Interleukin-2 for the Treatment of Cancer INNATE PHARMA S.A. (FR) 2010-07-29 US disclosed
WO-2010049438-A2 IMPROVED METHODS OF USING PHOSPHOANTIGENS FOR THE TREATMENT OF DISEASES INNATE PHARMA (FR) 2010-05-06 WO disclosed
EP-1569656-B1 PHOSPHOANTIGENS FOR REGULATING AN IMMUNE RESPONSE INNATE PHARMA (FR) 2010-03-03 EP disclosed
EP-2150258-A2 IMPROVED METHODS OF USING PHOSPHOANTIGENS TOGETHER WITH INTERLEUKIN-2 FOR THE TREATMENT OF CANCER Innate Pharma S.A. (FR) 2010-02-10 EP disclosed
US-20100029674-A1 Methods of Using Phosphoantigen for the Treatment of Cancer INNATE PHARMA, S.A. (FR) 2010-02-04 US disclosed
US-20090304688-A1 Methods and Compositions for Increasing the Efficiency of Therapeutic Antibodies Using Gamma Delta T Cell Activators INNATE PHARMA S.A. (FR) 2009-12-10 US disclosed
EP-2083830-A1 IMPROVED METHODS OF USING PHOSPHOANTIGEN FOR THE TREATMENT OF CANCER Innate Pharma (FR) 2009-08-05 EP disclosed
EP-2040750-A2 METHODS AND COMPOSITIONS FOR INCREASING THE EFFICIENCY OF THERAPEUTIC ANTIBODIES USING GAMMA DELTA T CELL ACTIVATORS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2009-04-01 EP disclosed
WO-2008059052-A9 IMPROVED METHODS OF USING PHOSPHOANTIGEN FOR THE TREATMENT OF CANCER INNATE PHARMA (FR) 2009-03-12 WO disclosed
EP-1948195-A2 IMPROVED METHODS OF USING PHOSPHOANTIGEN FOR THE TREATMENT OF CANCER Innate Pharma (FR) 2008-07-30 EP disclosed
WO-2008059052-A1 IMPROVED METHODS OF USING PHOSPHOANTIGEN FOR THE TREATMENT OF CANCER INNATE PHARMA (FR) 2008-05-22 WO disclosed
WO-2008006895-A2 METHODS AND COMPOSITIONS FOR INCREASING THE EFFICIENCY OF THERAPEUTIC ANTIBODIES USING GAMMA DELTA T CELL ACTIVATORS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2008-01-17 WO disclosed
US-20070134273-A1 Composition and method for the treatment of carcinoma ROMAGNE FRANCOIS 2007-06-14 US disclosed
WO-2007057440-A2 IMPROVED METHODS OF USING PHOSPHOANTIGEN FOR THE TREATMENT OF CANCER INNATE PHARMA (FR) 2007-05-24 WO disclosed
EP-1720567-A2 COMPOSITION AND METHOD FOR THE TREATMENT OF CARCINOMA Innate Pharma (FR) 2006-11-15 EP disclosed
US-20060194755-A1 Compositions and methods for regulating an immune response in a subject INNATE PHARMA, S.A.S. (FR) 2006-08-31 US disclosed
EP-1569656-A2 PHOSPHOANTIGENS FOR REGULATING AN IMMUNE RESPONSE Innate Pharma (FR) 2005-09-07 EP disclosed
WO-2005077411-A2 COMPOSITION AND METHOD FOR THE TREATMENT OF CARCINOMA INNATE PHARMA (FR) 2005-08-25 WO disclosed
WO-2004050096-A2 PHOSPHOANTIGENS FOR REGULATING AN IMMUNE RESPONSE INNATE PHARMA (FR) 2004-06-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100254940-A1 Compositions and Methods for Regulating an Immune Response in a Subject IFNG, IL2, ICOS BTN3A1 288/4885MVD 4043/4885FNTA 1683/4885
US-20100029674-A1 Methods of Using Phosphoantigen for the Treatment of Cancer CD4, CD74, TP53 BTN3A1 536/4885MVD 909/4885FNTA 3378/4885
US-20100189681-A1 Methods of Using Phosphoantigens Together with Interleukin-2 for the Treatment of Cancer IL2, IL2RA, CD4 BTN3A1 539/4885MVD 2950/4885FNTA 1180/4885
US-20070134273-A1 Composition and method for the treatment of carcinoma IFNG, IL2, PBK BTN3A1 155/4885MVD 2883/4885FNTA 219/4885
US-20060194755-A1 Compositions and methods for regulating an immune response in a subject IFNG, IL2, ICOS BTN3A1 279/4885MVD 4114/4885FNTA 1767/4885
US-20090304688-A1 Methods and Compositions for Increasing the Efficiency of Therapeutic Antibodies Using Gamma Delta T Cell Activators CD4, FCGR3B, IFNG BTN3A1 135/4885MVD 3676/4885FNTA 869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.