Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.65 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | KIF11 | P52732 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26827704 | 0.82 | MAOB (0.62) | KIF11MAOBKDM1APTPN1PTPN5 | |
| SCHEMBL12419569 | 0.82 | NPC1 (0.54) | MGLLMAOB | |
| SCHEMBL12419608 | 0.82 | MGLL (0.51) | MGLLCA1CA2KIF11MAOB | |
| SCHEMBL24106776 | 0.81 | KIF11 (0.67) | KIF11MAOBKDM1APTPN1PTPN5 | |
| SCHEMBL26821704 | 0.81 | KIF11 (0.67) | KIF11MAOBKDM1APTPN1PTPN5 | |
| SCHEMBL16068255 | 0.81 | KIF11 (0.67) | KIF11MAOBKDM1APTPN1PGR | |
| SCHEMBL6607384 | 0.81 | MGLL (0.86) | MGLLCA1CA2KIF11 | |
| SCHEMBL29678302 | 0.80 | TSHR (0.58) | MGLLKIF11MAOBKDM1APGR | |
| SCHEMBL1263144 | 0.80 | TSHR (0.58) | MGLLKIF11MAOBKDM1APGR | |
| SCHEMBL322980 | 0.79 | KIF11 (0.63) | KIF11MAOBKDM1APTPN1PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |