Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956955 | 0.88 | CA1 (0.44) | CA1CA2KDM4EALDH1A1MEN1 | |
| SCHEMBL29954445 | 0.79 | ENPP2 (0.49) | CA1CA2KDM4EALDH1A1MAPT | |
| SCHEMBL29953669 | 0.78 | CA1 (0.44) | CA1CA2KDM4EALDH1A1ENPP2 | |
| SCHEMBL2644418 | 0.78 | CA1 (0.44) | CA1CA2KDM4EALDH1A1ENPP2 | |
| SCHEMBL29951069 | 0.76 | CA1 (0.48) | CA1CA2KDM4EALDH1A1ENPP2 | |
| SCHEMBL13971022 | 0.74 | KDM4E (0.49) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL29957487 | 0.73 | CA1 (0.42) | CA1CA2KDM4EALDH1A1MEN1 | |
| SCHEMBL29957331 | 0.73 | CA1 (0.53) | CA1CA2KDM4EALDH1A1MEN1 | |
| SCHEMBL5782324 | 0.73 | CA1 (0.53) | CA1CA2KDM4EALDH1A1MEN1 | |
| SCHEMBL28736456 | 0.71 | ENPP2 (0.34) | CA1CA2ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |