Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956955 | 0.83 | CA1 (0.44) | CA1CA2ALDH1A1KMT2AKDM4E | |
| SCHEMBL29225972 | 0.78 | ENPP2 (0.46) | CA1CA2ALDH1A1KDM4EMAPT | |
| SCHEMBL29956833 | 0.77 | CA1 (0.42) | CA1CA2ALDH1A1KDM4ECA4 | |
| SCHEMBL29952765 | 0.75 | CA1 (0.46) | CA1CA2ALDH1A1KMT2AKDM4E | |
| SCHEMBL29952499 | 0.73 | CA1 (0.44) | CA1CA2ALDH1A1KMT2AKDM4E | |
| SCHEMBL29951489 | 0.73 | IRAK4 (0.39) | CA1CA2ALDH1A1KMT2AKDM4E | |
| SCHEMBL29957321 | 0.72 | NPC1 (0.37) | CA1CA2ALDH1A1KMT2AMEN1 | |
| SCHEMBL9389089 | 0.72 | LIPE (0.51) | CA1CA2ALDH1A1MAPTENPP2 | |
| SCHEMBL29957092 | 0.72 | CA1 (0.50) | CA1CA2ALDH1A1KMT2AKDM4E | |
| SCHEMBL28504374 | 0.72 | CA1 (0.50) | CA1CA2ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |