Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 11/20 | 0.44 |
| ▸ | PGR | P06401 | 5/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3276712 | 1.00 | NR3C2 (0.44) | NR3C2PGRNR3C1HTR1ADRD2 | |
| SCHEMBL5258793 | 0.86 | NR3C2 (0.43) | NR3C2PGRNR3C1HTR1ADRD2 | |
| SCHEMBL5340556 | 0.83 | IL4I1 (0.43) | NR3C2PGRNR3C1PDE3BPDE3A | |
| SCHEMBL4267822 | 0.81 | NR3C2 (0.47) | NR3C2PGRNR3C1HTR1ADRD2 | |
| SCHEMBL13932130 | 0.81 | NR3C2 (0.47) | NR3C2PGRNR3C1HTR1ADRD2 | |
| SCHEMBL5345549 | 0.81 | NR3C2 (0.43) | NR3C2PGRNR3C1PDE3BPDE3A | |
| SCHEMBL13950803 | 0.80 | NR3C2 (0.39) | NR3C2PGRNR3C1HTR1ADRD2 | |
| SCHEMBL705085 | 0.80 | NR3C2 (0.50) | NR3C2PGRNR3C1HTR1ADRD2 | |
| SCHEMBL532299 | 0.78 | ALDH1A1 (0.39) | PDE3BPDE3AMMP12ADRB2 | |
| SCHEMBL21372202 | 0.78 | NR3C2 (0.48) | NR3C2PGRNR3C1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |