Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29210595 | 0.80 | ALDH1A1 (0.38) | S1PR4ALDH1A1 | |
| SCHEMBL13233380 | 0.75 | ERN1 (0.33) | GAAS1PR4ALDH1A1 | |
| SCHEMBL13724582 | 0.75 | UHRF1 (0.54) | GAACYP3A4TSHRALDH1A1MAPK1 | |
| SCHEMBL29426583 | 0.75 | POLB (0.35) | GAAS1PR4CASP6ALDH1A1 | |
| SCHEMBL3718105 | 0.75 | POLB (0.35) | GAAS1PR4CASP6ALDH1A1 | |
| SCHEMBL24387499 | 0.75 | CYP3A4 (0.34) | S1PR4CYP3A4ALDH1A1 | |
| SCHEMBL29950966 | 0.75 | TSHR (0.36) | S1PR4TSHRALDH1A1HPGDHSD17B10 | |
| Formic Acid Methyl Ester SCHEMBL28084899 | 0.74 | NPC1 (0.34) | GAAS1PR4ALDH1A1 | |
| SCHEMBL9446708 | 0.72 | S1PR4 (0.38) | S1PR4CYP3A4ALDH1A1CA1CA2 | |
| SCHEMBL30983229 | 0.72 | CYP2A6 (0.39) | TSHRALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |