Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.50 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.45 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.45 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.45 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.45 |
| ▸ | PDE2A | O00408 | 4/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL581357 | 1.00 | MGLL (0.50) | MGLLTRPV6ORAI1ORAI2ORAI3 | |
| SCHEMBL4841354 | 0.85 | MGLL (0.48) | MGLLTRPV6ORAI1ORAI2ORAI3 | |
| SCHEMBL29427029 | 0.85 | MGLL (0.48) | MGLLTRPV6ORAI1ORAI2ORAI3 | |
| SCHEMBL1396618 | 0.84 | MGLL (0.52) | MGLLTRPV6ORAI1ORAI2ORAI3 | |
| SCHEMBL496773 | 0.81 | CES2 (0.50) | MGLLTRPV6ORAI1ORAI2ORAI3 | |
| SCHEMBL29508599 | 0.81 | MGLL (0.48) | MGLLTRPV6ORAI1ORAI2ORAI3 | |
| SCHEMBL15010827 | 0.81 | MGLL (0.48) | MGLLTRPV6ORAI1ORAI2ORAI3 | |
| SCHEMBL29755537 | 0.81 | PDE2A (0.50) | MGLLTRPV6ORAI1ORAI2ORAI3 | |
| SCHEMBL582110 | 0.81 | PDE2A (0.50) | MGLLTRPV6ORAI1ORAI2ORAI3 | |
| SCHEMBL29349652 | 0.81 | CES2 (0.50) | MGLLTRPV6ORAI1ORAI2ORAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215450-A1 | THIAZOLE COMPOUNDS AS SODIUM CHANNEL BLOCKERS | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2025-10-16 | — | — | WO | disclosed |
| EP-4590672-A1 | PHTHALAZINE DERIVATIVES USEFUL AS INHIBITORS OF NOD-LIKE RECEPTOR PROTEIN 3 | Merck Sharp & Dohme LLC (US) | 2025-07-30 | — | — | EP | disclosed |
| CN-119907797-A | Phthalazine derivatives as NOD-like receptor protein 3 inhibitors | 默沙东有限责任公司 | 2025-04-29 | — | — | CN | disclosed |
| WO-2024226603-A1 | THERAPEUTIC COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2024-10-31 | — | — | WO | disclosed |
| WO-2024064245-A1 | PHTHALAZINE DERIVATIVES USEFUL AS INHIBITORS OF NOD-LIKE RECEPTOR PROTEIN 3 | MERCK SHARP & DOHME LLC (US) | 2024-03-28 | — | — | WO | disclosed |
| WO-2022250104-A1 | QUINOLONE DERIVATIVE HAVING ANTIMALARIAL ACTIVITY | 国立大学法人長崎大学 | 2022-12-01 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |