Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3064197 | 1.00 | TSHR (0.65) | TSHRACHENFE2L2HSD17B10XDH | |
| SCHEMBL1548019 | 0.85 | CYP19A1 (0.50) | TSHRNFE2L2XDHCYP19A1ERN1 | |
| SCHEMBL348330 | 0.85 | CYP19A1 (0.56) | TSHRNFE2L2XDHCYP19A1ERN1 | |
| SCHEMBL16952282 | 0.82 | TSHR (0.63) | TSHRACHENFE2L2HSD17B10CYP19A1 | |
| SCHEMBL16959336 | 0.82 | TSHR (0.63) | TSHRACHENFE2L2HSD17B10CYP19A1 | |
| SCHEMBL635130 | 0.80 | TSHR (0.90) | TSHRACHEHSD17B10CYP19A1ALDH1A1 | |
| SCHEMBL1097495 | 0.80 | TSHR (1.00) | TSHRACHEHSD17B10CYP19A1ALDH1A1 | |
| SCHEMBL3065944 | 0.78 | TSHR (0.57) | TSHRACHENFE2L2HSD17B10ALDH1A1 | |
| SCHEMBL3065945 | 0.78 | TSHR (0.57) | TSHRACHENFE2L2HSD17B10ALDH1A1 | |
| SCHEMBL19199165 | 0.78 | NFE2L2 (0.69) | TSHRACHENFE2L2HSD17B10CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |