Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3065944 | 1.00 | TSHR (0.57) | TSHRMAPTMEN1KMT2ALMNA | |
| SCHEMBL16952282 | 0.80 | TSHR (0.63) | TSHRMEN1KMT2ALMNAHTT | |
| SCHEMBL31191248 | 0.79 | PTGS1 (0.51) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL3064197 | 0.78 | TSHR (0.65) | TSHRMEN1KMT2ALMNAHTT | |
| SCHEMBL29952610 | 0.78 | TSHR (0.65) | TSHRMEN1KMT2ALMNAHTT | |
| SCHEMBL4047776 | 0.77 | HTT (0.48) | MAPTKMT2AHTTALDH1A1L3MBTL1 | |
| SCHEMBL2161643 | 0.77 | HTT (0.48) | MAPTKMT2AHTTALDH1A1L3MBTL1 | |
| SCHEMBL2161647 | 0.77 | HTT (0.48) | MAPTKMT2AHTTALDH1A1L3MBTL1 | |
| SCHEMBL16959336 | 0.77 | TSHR (0.63) | TSHRMEN1KMT2ALMNAHTT | |
| SCHEMBL8888014 | 0.75 | ALOX5 (0.49) | MAPTMEN1KMT2AHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230913-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-18 | — | — | EP | disclosed |
| CN-101902915-B | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG | 2014-07-09 | — | — | CN | disclosed |
| US-8410145-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-02 | — | — | US | disclosed |
| CN-101902915-A | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG | 2010-12-01 | — | — | CN | disclosed |
| US-20100273832-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-28 | — | — | US | disclosed |
| EP-2230913-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009077197-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273832-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | TSHR 2638/4885MAPT 3827/4885MEN1 790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.