Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4243110 | 1.00 | MEN1 (0.55) | MEN1KMT2ANPC1RAB9ATDP1 | |
| SCHEMBL29954279 | 0.88 | KMT2A (0.55) | MEN1KMT2ANPC1RAB9ATDP1 | |
| SCHEMBL3790521 | 0.86 | ALDH1A1 (0.56) | MEN1KMT2ATDP1LMNATRPV1 | |
| SCHEMBL2560806 | 0.84 | TP53 (0.50) | MEN1KMT2ANPC1RAB9ATDP1 | |
| SCHEMBL2560439 | 0.81 | FADS1 (0.58) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15331049 | 0.80 | HPGD (0.55) | KMT2ANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL16033805 | 0.78 | PADI4 (0.55) | KMT2ASMN1; SMN2LMNATRPV1HTT | |
| SCHEMBL15219450 | 0.78 | MEN1 (0.58) | MEN1KMT2ANPC1RAB9ATDP1 | |
| SCHEMBL5786347 | 0.78 | KAT6A (0.58) | MEN1KMT2ANPC1RAB9ATDP1 | |
| SCHEMBL6812861 | 0.78 | MEN1 (0.58) | MEN1KMT2ANPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |