Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | FDPS | P14324 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958425 | 0.95 | ALDH1A1 (0.90) | ALDH1A1SMN1; SMN2POLBFDPSKDM4E | |
| SCHEMBL15331508 | 0.90 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2POLBFDPSKDM4E | |
| SCHEMBL2551892 | 0.89 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2POLBKDM4EMEN1 | |
| SCHEMBL29956279 | 0.87 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2POLBFDPSKDM4E | |
| SCHEMBL29951649 | 0.87 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2POLBFDPSKDM4E | |
| SCHEMBL2552984 | 0.86 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2POLBFDPSKDM4E | |
| SCHEMBL29953109 | 0.86 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2POLBFDPSKDM4E | |
| SCHEMBL2562037 | 0.86 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2POLBFDPSKDM4E | |
| SCHEMBL2558682 | 0.86 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2POLBFDPSKDM4E | |
| SCHEMBL2562872 | 0.86 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2POLBFDPSKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |